Pretty much every game using SCI1.1 and up was composed for General MIDI (SC-55 particularly) with MT-32 support added as an afterthought with a General MIDI-esque patch map. There are only a small few exceptions to this. Two being:
- Police Quest 1 VGA
- Laura Bow 2
Those are the only two I ever remember offhand that were composed for the MT-32 and General MIDI was added later and the game itself was released in SCI1.1 (may have started out life as SCI1.0 games). If there are more there aren't many. SC-55 quickly took over and MT-32 was left in the dust, to sometimes less than appealing results.
SQ4CD has the same sound files from SQ4 floppy. It uses a special driver that remaps the MT-32 instruments to General MIDI on the fly (and it doesn't do a very good job as many instruments are missing, including drum kits).
KQ5CD is interesting in that it's SCI1.0, but it has a Windows interpreter which means it must also support General MIDI (specifically Extended and Base MIDI). As such, every sound file numbered 1000 and up are GM Ext/Base MIDI duplicates of the MT-32 sounds numbered under 1000. (incidentally, SQ4CD also does this for its Windows version)
SQ5 was made by Dynamix who used their own General MIDI MT-32 patch map with slightly better results than Sierra's.
Eco Quest 1 was released on both SCI1.0 and SCI1.1. The SCI1.0 version obviously supports only MT-32 (logically) so that's what it was composed for.
QFG1VGA uses the MT-32 sound files from the original game but also had new music written for it that's not in the EGA original. I'm unsure at the moment if these pieces were composed with the MT-32 or General MIDI. My guess is the latter.
That's all the edge cases I can think of right now. Basically, if it started life as an SCI1.0 game then it was composed for the MT-32. This is mostly obvious except in PQ1VGA's and LB2's cases.
Also, it may interest some here that on the Space Quest Historian Discord server we've started a community Google spreadsheet to chart every MIDI sound file in all the SCI games. The purpose being to identify which sound resources are which themes to make it easier to pick out the themes you're looking for easier. It's a community spreadsheet which means anyone can help go through the resources with SCI Viewer or Companion, listen to each resource, and mark down the song titles for each game. For bonus points, you can search the decompiled game scripts to find which scripts trigger each sound file. We've got a few games completed already for reference. You can also see in SQ4CD and KQ5CD's cases where the Windows duplicate sound resources start. It also lists for each game which device it was composed with/sounds best on.
https://docs.google.com/spreadsheets/d/1ECMTncmqfG__6lY5v5v1JhkviC8pxW_v0sX_ILwS-ZI/edit?usp=sharing