Of course it has .NET dependencies. it was written in C#. The Microsoft Active Accessibility is really only needed for older versions of Windows. Were you trying to run it with WINE? One of the Linux users here may have some information on running .NET apps on Linux.
Hm, wouldn't you find it ironic: "The Microsoft Active Accessibility is really only needed for older versions of Windows" ?
We are supporting AGI from 1984., but not MAA (1997) needed for Win95.

New ARMs are fast & strong enough to emulate Win95 but not Win7.
Never mind.
Well, I tried to run it with WINE several times, no success. There are couple of .NET apps I'm running with WINE. Unfortunately, VAGI is not one of them.
I'm not sure what's wrong, because
WINE has "gold"/"platinum" status for most .NET Frameworks versions.
Probably something related to this:
"Always install with recent 'winetricks' in clean 32-bit wineprefix for best results."
(64-bit environment is not supported at some things as it should be)
I did this but... didn't work. I tried also with "PlayOnLinux" (>some kind of Wine pre-set installers);
here is some others example what's going on.
http://lookpic.com/O/i2/524/jmbWF1vi.pngHere is screenshot of what's going on: winetricks for .NET installer (e.g. v 2.0) claims that mono is not installed (which is), and right after that "64-bit is not supported" (it is not 64-bit). However, I have .NET 4.0 installed, some software is running flawlessly. But VAGI just won't start, no error messages.
Of course, I could run it through some virtual box, probably. But it is... humiliating.
e. g. I'm running Photoshop CS2-6 w/o problems.